WRN and Werner syndrome: Array-based genome wide DNA methylation profiling of HGP and WS patients with either causative mutations in the LMNA and WRN genes or unknown etiology revealed aberrant DNA methylation and global DNA methylation differences with DNA hypomethylation and hypermethylation signatures between LMNA mutant, WRN mutant and non-mutant patients that also affect genes involved in aging processes [28].