Thyrospheres generated from primary thyroid cancer cells expressed ALDH1A1 and CD44 (6), and some expressed stemness markers, Oct-4, ATP-binding cassette sub-family G member 2 (ABCG2), Sox-2, Nanog, CD133, and CD44 (7, 10, 11). Here, ALDH1A1 is linked to thyroid gland carcinoma.