NTRK2 and Cockayne syndrome type 2: Therefore, to further expand on the finding that CSB function can be bypassed with TrkB agonists in neuroblastoma cells and ReNcell VM cells, we derived neurons from CSB patient-derived iPSCs and cultured these for 1 week in the absence or presence of TRKB agonists amitriptyline or 7,8-DHF.