This resulted in a significant inhibition of MYB target genes and proliferation of cylindroma cells from three independent tumours, suggesting that MYB activation drives the growth of CYLD‐defective cylindromas and potentially also the growth of MYB–NFIB‐positive sporadic cylindromas. The gene discussed is NFIB; the disease is adnexal spiradenoma/cylindroma of a sweat gland.