REN and benign prostatic hyperplasia: REN and KLKB1 mRNA expression data were collected and analyzed for in mouse As4.1 cells (Fig. 6a) and adrenal tissues of rodent genetic hypertension models: blood pressure low (BPL) and blood pressure high (BPH) mouse models and normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rat models (Fig. 6b).