GPT and hypohidrotic ectodermal dysplasia: The serum AST and ALT levels of the HED rats were dramatically elevated (P < 0.0001) to 80 ± 11 and 33 ± 9 U/L, respectively, compared to those of rats in the vehicle group, which were 63 ± 10 and 20 ± 3 U/L, respectively.