ASPG and osteonecrosis: A multivariate analysis including plasma dexamethasone and asparaginase levels suggested that dexamethasone (OR = 1.01 for every 1 nmol/L increase, P = 0.029) and asparaginase concentrations (OR = 1.06 for every 1 IU/mL increase, P = 0.002) were both independently associated with osteonecrosis.