It is also possible that, as we recently described in the breast cancer setting, asTF modulates binding and/or migration on laminin, similarly to how flTF modulates migration on laminin [8]; an even more intriguing scenario might be envisioned whereby asTF competitively removes flTF-dependent inhibition of β1 integrins on laminin. The gene discussed is LAMB2; the disease is breast carcinoma.