TWF1 and breast cancer: Because asTF- α6/β1 integrin interactions promote breast cancer cell proliferation [8], we sought to determine whether this enhanced scratch closure was mainly due to enhancement of PDAC cell migration rather than cell proliferation; thus, we performed a 5-hour cell migration assay under a serum chemo-gradient using laminin-coated transmembrane inserts and Pt45.P1/asTFi cells.