In CML, abnormal expression of miR-29 family has been described [69] and a recently performed qPCR analysis of miR-29b expression further suggested that miR-29b was significantly downregulated in CML patient samples, suggesting that miR-29b negatively regulates ABL1 and BCR/ABL1, post transcriptionally [70, 71]. This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.