Leukotriene D4 (LTD4) stimulates the proliferation of endothelial cells through cysteinyl leukotriene receptor 1 (CysLT1R) [65], which was shown expressed highly in many cancers (e.g., prostate cancer, brain cancer, neuroblastomas, and CRC) [66]. Here, CYSLTR1 is linked to Familial prostate cancer.