In conclusion, the present findings support previous evidence that homozygosis for risk allele A of SNP rs1344706 of ZNF804A confers risk for SZ and BD, and impaired functional connectivity (Esslinger et al., 2011; Walter et al., 2011; Paulus et al., 2013), by offering a possible pathophysiological mechanism whereby this genetic variant promotes reduced WM integrity in a widespread network. The gene discussed is ZNF804A; the disease is Behcet disease.