The concept that tumor cells alter their gene expression profiles to acquire a genophenotype closely resembling that of platelets and express several megakaryocytic genes (adhesion receptors αIIbβ3, thrombin receptor, and PECAM/CD31 and/or platelet-type 12-LOX) to activate platelets or the coagulation cascade is referred to as “platelet mimicry” of tumor cells [102]. Here, F2R is linked to neoplasm.