Thus, for the most common subtypes, the rate of disease control (CR/CRu + PR + SD90) was 49 % (34/69) for PTCL-NOS, 44 % (12/27) for AITL, and 38 % (8/21) for ALK-1-negative ALCL. This evidence concerns the gene ALK and mature T-cell and NK-cell non-Hodgkin lymphoma.