ADIPOQ and coronary artery disorder: ADIPOQ rs1501299 is association with CAD, and the SNP has different gender dependent effect on adiponectin levels and the lipoprotein metabolism, considering the detrimental effect that the rare homozygous genotype (TT) was associated with higher levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) compared to common homozygous genotypes (GG) and heterozygous, and the polymorphism influence on the levels of biochemical markers was independent of adiponectin circulating level [20, 21].