Although the Lhfpl2 MUT infertile males at 6-month old had slightly lower body weight and testis weight than their age-matched control males (see Supplementary Fig. S4a,b), their relative testis weight was comparable with that of the control (see Supplementary Fig. S4c) and there was no significant difference in the sperm counts from cauda epididymis (see Supplementary Fig. S4d) or the testis histology (Fig. 5d,e) between WT and sterile MUT males. The gene discussed is LHFPL2; the disease is Infertility.