To assess the importance of aggNETs to human pancreatic diseases, we next studiedsamples from patients with benign- or malignancy-related pancreatitis using bothhistological tissue sections and endoscopy-derived samples of pancreatic juice.Several samples of inflamed human pancreatic tissue displayed MPO- andH3cit-positive intraductal neutrophil aggregates (Fig.3a). This evidence concerns the gene MPO and pancreatitis.