In the univariate logistic regression analyses, we found a high dioxin level was associated with an OR of 7.40 (95% CI: 4.78–11.45) for CKD in comparison with a lower dioxin level, and other potential risk factors included female gender, MS, DM, hypertension, high insulin, high uric acid, and age above 40 years. This evidence concerns the gene INS and hypertensive disorder.