When compared with normal controls, TREM-1 expression levels were approximately 12-fold higher in the early stage and 40-fold higher in the late stage of fungal keratitis (both P<0.001), while Dectin-1 expression levels were 8-fold higher in the early stage and 30-fold higher in the late stage (P<0.01 and P<0.001, respectively). This evidence concerns the gene CLEC7A and fungal keratitis.