Notable associations encoding amino acid variations were found (where the OD4 SNP:amino acid postion:CJ994 SNP) in the ICP4 (M454L; blepharitis and stromal keratitis), US3 (T52P; blepharitis and stromal keratitis), gG (K96E, V113F, G117E, V119D, P131S, G133D, S152I, Q163R; blepharitis and stromal keratitis), and VHS (L374R, N384S, fs*475P; stromal keratitis) proteins. The gene discussed is RPS3; the disease is blepharitis.