Finally, a pleural fluid cathepsin-B level <0.31 ng/mL yielded 89% sensitivity (95% CI 65.3–98.6%), 62% specificity (95% CI 43.6–77.8%), LR positive of 2.3 (95% CI 1.5–3.7), and LR negative of 0.18 (95% CI 0.05–0.68) for separating 18 lymphomas from 34 TB (Table 3). The gene discussed is CTSB; the disease is lymphoma.