CTSB and lymphoma: In particular, patients who scored 2 points, in which 1 point each was assigned to both pleural fluid cathepsin-B concentrations <0.31 ng/mL and age ≥50 years, were most likely to have lymphomas rather than TB (sensitivity 72.2%, 95% CI 46.5–90.3%; specificity 100%, 95% CI 89.7–100%; LR positive 25.3, 95% CI 3.6–178.2; LR negative 0.28, 95% CI 0.13–0.59; and AUC 0.94, 95% CI 0.88–0.99).