Increasing age is associated with the emergence of MS and IR, and not only with the natural, and highly variable, course of HCV chronic infection.44 A high plasma triglyceride level is one of the most conspicuous metabolic findings in MS,8 whereas high uric acid levels are frequently found in MS and linked to insulin sensitivity index, probably through its close relationship with triglyceride levels,45 thus explaining why uric acid it is in the limit of significance in the multivariate analysis and excluded from the predictive model for IR that we propose in this study. The gene discussed is INS; the disease is myeloid sarcoma.