The carrier state of the rs738409G allele of the PNPLA3 gene was not related with presumptive inflammatory markers, both direct (LBP, IL-6, and serum cystatin C), and inverse (prealbumin and RBP4), nor with metabolic parameters related to the metabolic syndrome (blood lipids, uric acid, serum ferritin, TSH, and T4) (data not shown). The gene discussed is PNPLA3; the disease is metabolic syndrome.