Anti-RNP antibody and Raynaud's phenomenon (RP) were believed to be associated with this subtype,14,19,34,42 and RP was also proved as an indicator of disease severity.36,38,42–44 Percentage of RP in our study was 64.5%, in accordance with previous published data;45 however, we lack the data of the control group. The gene discussed is RNPC3; the disease is retinitis pigmentosa 1.