Figure 2 shows a stacked bar chart of these pathways and other significant pathways considered to be relevant to the pathogenesis of malaria: Cytotoxic T lymphocyte-mediated apoptosis of target cells (11th ranked pathway in terms of significance), dendritic cell maturation (13th), T cell receptor signaling (14th), T helper cell differentiation (18th), and IL-10 signaling (20th) [27]. This evidence concerns the gene IL10 and malaria.