Having established that MØ and milk-derived cells from BS cows seem to produce more ROS/RNS compared to cells derived from HF cows, we next wanted to establish whether this increased reactivity is a general sign for an increased innate immune response in BS derived cells, and extends to other mediators of the innate immune response, such as production of IL-1β. The gene discussed is IL1B; the disease is hydrops fetalis.