However, elevated p-STAT3 (OR = 2.45, 95% CI = 1.73 to 3.46, P < 0.00001) expression in tumor tissue seemed to be more significantly associated with worse 3-year OS than STAT3 expression (OR = 1.72, 95% CI = 1.10 to 2.70, P = 0.02) (Supplementary Figure S5). Here, STAT3 is linked to neoplasm.