For example, the expression levels of miRNA-181a, miR-155, miR-150, miRNA-221, miR-106a, miRNA-221, miR-146a and miR-146b were increased in OVA-induced mouse model of asthma [15–18]; the miR-126, miR-145 and miR-106a expression levels were increased in house dust mite (HDM)-induced experimental asthma model [19–21]; and miR-21 was up-regulated in lung-specific interleukin (IL)-13-induced asthma model [22]. The gene discussed is IL13; the disease is asthma.