In fact, recent studies reported that CB suppresses cell proliferation and induces cell cycle arrest and apoptosis through downregulation of p-ERK, c-MYC, p-GSK-3β, NK-κB/p65, and p38 MAPK, but upregulation of intracellular free calcium ([Ca2+]i) and Cyclin A in cancer cells [19, 24, 46, 47, 52–54]. Here, GSK3B is linked to cancer.