SIRT1 and colorectal carcinoma: CRC cells (HCT116 and SW480) either served as controls or were transfected with 0.5 μM Sirt1-SO or Sirt1-ASO in the presence of Lipofectin for 24 h and co-treated with resveratrol (5 μM) for an additional 24 h, and surviving colonies were collected.