To identify the involvement of glycosphingolipids in adhesion capacities of breast cancer cells to BBB ECs, their biosynthesis was inhibited using D-L-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP), a chemical glucosylceramide synthase inhibitor [19]. The gene discussed is UGCG; the disease is breast carcinoma.