In contrast to the anti-ACTL7a antibodies, the average concentrations of the anti-ACTIN antibodies declined from 0.23 ± 0.01 × 10−1 μg/μL in fertile sera to 0.16 ± 0.01 × 10−1 μg/μL in infertile sera (P < 0.0001, Fig. 1a). Here, ACTL7A is linked to Infertility.