In striking contrast with that observed for CORT, lack of endogenous SST did not influence DMBA-induced tumorigenesis in lean mice compared with WT controls, as only 4.34 % of LF-fed SST-KO mice developed mammary tumors, a similarly low percentage to that observed in LF-fed WT mice and substantially lower than in LF-fed CORT-KO animals (Fig. 2a). This evidence concerns the gene CORT and breast cancer.