There were fewer newly diagnosed patients in the AZL-M group (34.2 % vs. 43.9 %), and those with established hypertension had a longer mean time since diagnosis in comparison to the ACE-inhibitor group (67.2 ± 65.3 months vs. 57.7 ± 60.9 months; p < 0.001). This evidence concerns the gene ACE and hypertensive disorder.