Further KM survival analysis revealed that the Log-Rank P values of CDCP1, IGF2R, IRAK3, LATS2, PIK3CB, ULK4, and VRK1 were < 0.05 (Figure 4B and Supplementary Figure S2), suggesting that the expression of these SGKs in the newly diagnosed GBM has a statistically significant correlation with the patient survival associated with recurrence. The gene discussed is PIK3CB; the disease is glioblastoma.