There were more than 8% of cases with a higher protein level of 12 SKGs (CDCP1, CDKL5, CSNK1E, IGF2R, IQCD, MAP4K3, MELK, NEK9, STK3, TBRG4, ULK4, and VRK1) in glioma (Figure 2C, grey bars). This evidence concerns the gene TBRG4 and central nervous system cancer.