Furthermore, NSG mice injected with ARC KD Molm13 cells had approximately half of human IL1β concentration in their serum (Figure 4C), while the leukemia burden was about 30% less in these mice compared to the mice injected with control Molm13 cells after three weeks [28], suggesting that ARC may exert some of its function through IL1β signaling. Here, ARC is linked to leukemia.