Previous studies have shown that the number of infiltrated CD8+ T cells is a good prognostic factor in human colorectal cancer [16–18], while a high density of tumor-infiltrating FOXP3+ Treg cells is associated with poor outcome in a number of solid cancer types, including ovarian [19], pancreatic [20], and hepatocellular carcinomas [21, 22]. This evidence concerns the gene FOXP3 and neoplasm.