IL10-deficient Kras4bG12D- and EGFRL858R-induced lung cancer mice (Scgb1a1-rtTA/TetO-Kras4bG12D/IL10−/− and Scgb1a1-rtTA/TetO-EGFRL858R/IL10−/−) were established for this purpose (Figure 3). Here, SCGB1A1 is linked to lung carcinoma.