SLC6A6 and homocystinuria: Furthermore, TauT-mediated cell taurine influx might be modulated by intracellular synthesis of taurine originating from the transsulfuration pathway of homocysteine to cysteine and then to taurine [32], while, conversely, taurine supplementation might increase homocysteine metabolism, as happens in mice with cystathionine β-synthase-deficient homocystinuria [33].