NFKB1 and cancer: Among the top 10 enrichment score values, 16-day TGF-β1 treatment greatly reduced the pathways of cell cycle, DNA replication, and metabolism of xenobiotics by cytochrome P450, which is consistent with our previous results where TGF-β1 impaired the proliferation and differentiation capacity but increased pathways involved in cancer, ECM-receptor interaction, and NF-κB signaling if compared to control oval cells (Figure 6).