Together with T-cell acute lymphocyticleukemia 1 (TAL1) and RUNX1, GATA3 forms an autoregulatory loop that positively regulatesthe v-myb avian myeloblastosis viral oncogene (MYB) oncogene, which in turn controls thegene expression program in T-cell acute lymphoblastic leukaemia (T-ALL) (Ref. This evidence concerns the gene GATA3 and acute lymphoblastic leukemia.