87). Retained GATA6 expression has beenshown in gastric, colorectal, esophageal, ovarian and pulmonary cancer cell lines (Refs78, 88, 89, 90). Additionally, intestinal GATA6 expression is higher in proliferatingprogenitor cells compared with differentiated cells (Ref. 91). In primary gastric cancer, the pro-oncogenic effects of GATA6are recently confirmed, in vitro and in vivo (Ref. 92). This evidence concerns the gene GATA6 and gastric cancer.