By contrast, Ad-EGFP group tumors showed 7.0 fold increases in tumor volume (P > 0.05) and a single intratumoral injection of Ad-RAD50 induced a significant suppression of tumor growth relative to controls, with 5.23 fold increase in tumor volume (P > 0.05, Fig. 7-c). The gene discussed is RAD50; the disease is neoplasm.