Apart from AQP4-IgG, AQP1-Ab and MOG-IgG other antibodies might be detected in NMO/NMOsd patients, e.g., antibodies against N-methyl-d-aspartate-type (NMDA-type) glutamate receptor, against collapsin response mediator-protein 5 (CV2/CRMP5) and against glycine receptor [57]. This evidence concerns the gene AQP4 and neuromyelitis optica.