Other factors found in sera or in the CSF of some NMO patients are: IL-1 receptor antagonist (IL-1ra), IL-6, IL-8 (CCL8), IL-13, granulocyte colony-stimulating factor (G-CSF), High Mobility Group Box 1 Protein, B lymphocyte chemoattractant (BLC, CXCL13), interferon-gamma-inducible protein-10 (IP-10, CXCL10), and IL-13—responsive chitinase [57]. This evidence concerns the gene CXCL13 and neuromyelitis optica.