For example, upregulation of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been found to play an important role in NSCLC and originally identified as a potential marker for metastasis and patient survival in NSCLC, especially in early stages of lung adenocarcinoma in the early years[19, 20]. The gene discussed is MALAT1; the disease is lung adenocarcinoma.