AKR1B10 and hepatocellular carcinoma: Consistent with a recent report that AKR1B10 is involved in hepatocarcinogenesis by modulating cell proliferation and apoptosis5, we found that co-culture of QSG-7701 (human hepatocyte) with HepG2 (hepatoma cell line) increases QSG-7701’s proliferation, and this increase is modulated by a higher level of cellular AKR1B10 in HepG2 than in QSG-7701.