The association of PLG with LDL-C and CAD is interesting: prospective studies and clinical trials show consistent associations of plasminogen with lipid levels (Crutchley et al. 1989) and CAD risk (Baigent et al. 1998; Lowe et al. 2004; Sakkinen et al. 1999). The gene discussed is PLG; the disease is coronary artery disorder.