The seven tumors with <90 % positivity for E-cadherin were positive for the markers EMA (1 tumor; 100 % of cells detected), αvβ6 integrin (3 tumors; 78–93 % of cells detected), EpCAM (1 tumor; 81 % of cells detected), E-cadherin (1 tumor; 80 % of cells detected), and Her2neu (1 tumor; 76 % of cells detected). The gene discussed is ERBB2; the disease is neoplasm.