In addition, further mutations in other genes, such as CBL, CHEK2, DNMT3A, ASXL1, EZH2, IDH1/2, SF3B1, SH2B3 (LNK), SETBP1, SRSF2, and TET2, have been found in MPN [4–7]. Here, SH2B3 is linked to myeloproliferative neoplasm.