For a multivariate logistic regression model (including age class, splenomegaly, Jak2 status, high leukocytes, high platelets, cancer) to predict thrombosis/thromboembolism in our cohort, only splenomegaly was detected to have a significant effect on the prediction of thrombosis/thromboembolism (p = 0.0009 in maximum likelihood test). The gene discussed is JAK2; the disease is cancer.