Given that the majority of the genes within the ElasticNet derived genelist are involved in immune response and the previously discussed high levels of immune cell infiltrate observed in BRCA1-mutant and TNBC, the next obvious step was to investigate whether the tumour microenvironment of these tumours was different for the “NFκB on” vs “NFκB off” tumour sub groups. The gene discussed is BRCA1; the disease is neoplasm.