In order to develop a tumour derived classifier gene signature to identify the BRCA1-/NFκB+ subgroup, an ElasticNet computational analysis was applied (Supp Figure 2B(iii) and Supp Table 1) and further refined based on most statistically significant fold changes (Supp Figure 2B(iv) and Supp Table 2) comprising of 42 genes most of which (39/42g) are upregulated in the “NFκB on” subgroup. The gene discussed is NFKB1; the disease is neoplasm.