PIN1 and lymphoma: We further examined a set of 80 genes that were Myc-bound and strongly induced in Eμ-myc B cells [40]: as above, induction of these genes was reduced - albeit still detectable - in pre-tumoral Pin1−/− B cells, but was fully restored in Pin1−/− lymphomas (Figure 4D, 4E), indicating that Pin1 was not required for Myc transcriptional activity per se.