MMP9 and bladder transitional cell carcinoma: Because Endo et al [16] demonstrated that matrix metallopeptidase 9 (MMP9) is modulated by miR-596 in oral squamous cell carcinoma cell lines, we hypothesized that uc.8+ may regulate the expression of MMP9, a mesenchymal marker that is overexpressed in muscle-invasive BlCa cells, via binding to miR-596.