Date shown in Table 1 indicated that the positive expression of DR5 in patients with LNM was lower than those without LNM (p=0.002); besides, NPC patients in the later stage (III and IV) showed lower DR5 expression than NPC patients in the early stage (I and II) (p=0.011). This evidence concerns the gene TNFRSF10B and nasopharyngeal carcinoma.